Stem Cell Research & Treatment

Stem Cell Treatment

Stem Cell research is widely thought to be the cornerstone of medicine in the very near future. Whilst stem cells from teeth are not used routinely in medical treatments today, experts believe that one day they could be used to treat many different diseases and injuries. A small selection of research using stem cells from teeth and their potential to treat a variety of disorders is listed here to give you a deeper understanding of the significance of stem cells from teeth.

A comprehensive review of research relating specifically to stem cells from teeth can be downloaded below.

Publications on Therapy DPSC 2015
Publications on Therapy MSC April 2015
Support Evidence for Dental Pulp Stem Cells 2015

Stem Cell Research

The continuous advancement in stem cell research around the world means scientists are well down the path to curing diseases and healing medical conditions that would otherwise remain untreatable.

For stem cell treatment to work however, it is imperative that the source of the stem cells is compatible with the recipient and to avoid the rejection of transplanted tissues, it is always best to use the patient’s own stem cells for these treatments.

The cells found in teeth hold the potential to treat conditions such as:

  • Type 1 diabetes
  • Neuronal degenerative disorders (Alzheimer’s, Parkinson’s and Huntington’s disease)
  • Cardiovascular disease
  • Paralysis due to spinal cord injury
  • Liver disease
  • Stroke
  • Heart attack
  • Joint bone repair

As medical research continues to make amazing breakthroughs, storing teeth cells from your child is an excellent way to prepare for the healthcare needs they may encounter in their adult life.

BioEden's research and treatment

Stem Cell Treatment Breakthroughs

Type 1 Diabetes and prevention of diabetic retinopathy
Read about … Systemic administration of multipotent mesenchymal stromal cells reverts hyperglycemia and prevents nephropathy in type 1 diabetic mice
Parkinsons Disease
Read about … Stem cells from human-exfoliated deciduous teeth can differentiate into dopaminergic neuron-like cells.
Stroke (cerebral ischaemia)
Read about … Potential role of dental stem cells in the cellular therapy of cerebral ischemia.
Heart Attack
Read about … Human dental pulp stem cells improve left ventricular function, induce angiogenesis, and reduce infarct size in rats with acute myocardial infarction.
Liver disease
Read about … Multipotent cells from the human third molar: feasibility of cell-based therapy for liver disease.
Immune disorders
Read about … Immunomodulatory properties of stem cells from human exfoliated deciduous teeth.
Age related degenerative disorders
Read about … Human tooth germ stem cells preserve neuro-protective effects after long-term cryo-preservation.
Burns and tissue repair
Read about … More insight into mesenchymal stem cells and their effects inside the body.
Corneal reconstruction
Read about … Corneal reconstruction with tissue-engineered cell sheets composed of human immature dental pulp stem cells.
Repair of the central nervous system
Read about … Putative dental pulp-derived stem/stromal cells promote proliferation and differentiation of endogenous neural cells in the hippocampus of mice.
Read about … Isolation of distinct progenitor stem cell populations from dental pulp.
Repair of nerve and vascular tissue and treatment of neurological disease
Read about … Isolation and characterization of stem cells derived from human third molar tooth germs of young adults
Read about … Implanted adult human dental pulp stem cells induce endogenous axon guidance.
Read about … Simultaneous PKC and cAMP activation induces differentiation of human dental pulp stem cells into functionally active neurons.
Read about … Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues.
Bone growth and repair including facial reconstruction
Read about … A feasibility of useful cell-based therapy by bone regeneration with deciduous tooth stem cells, dental pulp stem cells, or bone-marrow-derived mesenchymal stem cells for clinical study using tissue engineering technology.
Read about … Differentiation potential of STRO-1+ dental pulp stem cells changes during cell passaging.
Read about … Addition of mesenchymal stem cells to the scaffold of platelet-rich plasma is beneficial for the reduction of the consolidation period in mandibular distraction osteogenesis.
Read about … Osteogenic capacity of human deciduous dental pulp stem cells in vitro
Read about … Human mandible bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes.
Read about … Stem cells from deciduous tooth repair mandibular defect in swine.
Read about … SHED repair critical-size calvarial defects in mice.
Read about … Reconstruction of large cranial defects in nonimmunosuppressed experimental design with human dental pulp stem cells.
Read about … Dental pulp stem cells: a promising tool for bone regeneration.
Read about … For the first time in Mexico, surgeons implant stem cells obtained from wisdom teeth
Tissue engineering and plastic surgery
Read about … Human dental pulp stem cells: from biology to clinical applications.
Read about … In vivo evaluation of human dental pulp stem cells differentiated towards multiple lineages.
Read about … Transplantation of mesenchymal stem cells is an optimal approach for plastic surgery.
Dental treatments
Read about … Dental stem cell therapy with calcium hydroxide in dental pulp capping.
Read about … Dental tissue regeneration – a mini-review.

DID YOU KNOW?

Stem cell therapy has been used successfully thousands of times in many countries around the world. Stem cells have been successfully used to grow replacement skin, tracheas, and corneas as well as offer heart repair after a heart attack. It is widely believed that stem cell therapy may offer remedies for such conditions such as Parkinson’s, Alzheimer’s disease, juvenile diabetes, spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis, and certain forms of cancer.