Frequently
Asked
Questions

Find out more about storing tooth cells with BioEden

Stem cell therapy is emerging as a revolutionary new way to treat disease and injury, with wide-ranging medical benefits. It works by introducing stem cells into an area where the normal cells have lost their function due to disease or damage. The stem cells then replace or repair the damaged cells and restore normal function.

Getting started

Why do we need a small blood sample and when?

We are regulated by the Human Tissue Authority (HTA) in the UK and as such are obliged to receive a small blood sample from your child to test for HIV, Hepatitis B, Hepatitis C and Syphilis within 7 days of the tooth falling out. This is a standard blood screening and helps to further secure your child’s sample for future use.

My child’s tooth is now loose. What should I do?

As soon as you’ve become a member with BioEden, we’ll send you a collection kit containing all the instructions and information you’ll need to help preserve the tooth cells.

How much does it cost?

See our pricing section for membership options.

Tooth Collection

My child’s tooth is now loose. What should I do?

As soon as you’ve become a member with BioEden, we’ll send you a collection kit containing all the instructions and information you’ll need to help preserve the tooth cells.

How do I get my child’s tooth to you?

Yes, but not harvested stem cells. The collection pack we send you once you’ve enrolled contains instructions on how to send us the tooth.

Where can I get an information pack?

Information Pack

Sending

Storage & Retrieval

What temperature will my child’s cells be stored at?

Once extracted from the tooth pulp and tested for viability, the cells are stored at -196.5 degrees centigrade

How do you guarantee my child’s cells are secure and all the information I give you is confidential?

Our laboratory is within a high protection building with 24 hour security personnel and limited access. As soon as we receive your tooth cell storage order, we allocate you with a unique customer reference number also featuring your child’s name and date of birth.

How long do you store the cells for?

Your tooth cell samples are stored for as long as you maintain your contract with us.

Can I donate some of my child’s cells to research?

When you apply for BioEden membership, you will be offered the opportunity to consent to donate any excess tooth cells. BioEden will provide these cells to leading academic and clinical research centres to help further the progression of this technology to useful clinical applications. BioEden will only provide cells to researchers that have full ethical approval for their research and will be guided by our Advisory team as to the most appropriate research to support. The cells will be donated in accordance with strict regulatory guidelines and anonymity of the donor will be strictly assured at all times.

Donation of cells is an entirely opt in service. If you choose not to give consent to donate, BioEden will simply store the cells for your child.

What happens if I need access to the tooth cells?

You will need to complete a form to request the cells and a second form will be required from the consignee (person/centre receiving the cells). The consignee will be responsible for collecting the cells.

What happens if I stop paying my membership?

We reserve the right to remove the cells from storage.

What do you do with my child’s tooth cells over the years?

We store the cells on the registered child’s behalf, and we continue to do so for as long as you maintain your contract with us.

What is the process?

Don’t wait until your child starts to lose their teeth before you make your decision. Join now and follow our simple 3 step process to ensure you’re immediately prepared to safely return the teeth to our nearest laboratory.

Always ensure that your child brushes their teeth regularly, (at least twice a day) and uses a mouthwash.

Step 1 – Tooth Collection

Join now, and we will send you a tooth collection kit. The tooth collection kit includes easy to follow instructions. Please read these prior to the tooth falling out or being extracted. The time immediately after the tooth has fallen out or has been extracted is critical.

Carefully following the instructions, the tooth must be placed and packaged in the collection box provided. You then contact us, and we arrange for the kit to be shipped and received at the BioEden laboratory within 48 hours to maximise chances of a successful isolation of the valuable tooth cells.

Within 7 days of the tooth falling out, please arrange a blood sample taken from your child and returned to us in the provided blood collection packaging.

Step 2 – Tooth Cell Isolation

When the tooth is received at the laboratory, our scientists work swiftly to collect the cellular material. Once the tooth cells are isolated, we confirm the health and viability of the cells.

Step 3 – Tooth Cell Storage

Once we have a guaranteed number of viable, uncontaminated tooth cells, suitable for healthy growth and future treatment, they are cryogenically stored for your family’s future. Every tooth cell batch is divided into two separate samples, then cryopreserved.

Our patented process allows us to keep these valuable tooth cells stored well into the adult life of the donor. This secures the potential for the treatment of illness and disease at a time when they are needed most.

We understand your continued interest in your investment, so we continually update all our customers on the latest advances in the field of stem cell research and application. We also regularly check all our processes to ensure we constantly maintain standards and operate within stringent regulatory guidelines.

BioEden Process

What makes BioEden Different?

BioEden were the world’s first tooth cell bank, and remain the only specialist bank in the UK. We pioneered the science of extracting cells from teeth and our simple process is unique and patented.

Some companies simply store the tooth, whilst others store the dental pulp. At BioEden we go a step further, extracting the cells from the pulp before cryopreserving them. We perform annual validation to ensure our process can isolate cells from teeth that test positive for Mesenchymal stem cell markers.

Why settle for anything less than the best?

What happens if I fail to supply a blood sample within 7 days of supplying the tooth?

It is required by EU and UK law that BioEden obtain and test a blood sample for each donor within 7 days of tooth donation and there can be no deviation from this time line. Any customer for which we are unable to obtain a usable serology test results within the required time will have their samples discarded and they will not be entitled to a refund.

Do you inform me after freezing my child’s tooth cells?

Yes, we send you a certificate verifying your child’s tooth cells have been successfully stored.

What cells are found in teeth?

About tooth cells

Stem cell therapy, without the fear of rejection, offers one of the most promising paths to curing medical conditions, injures and diseases and safeguarding the health of future generations. An ongoing supply of healthy cells is therefore essential.

In humans, stem cells can be found in many different parts of the body, typically bone marrow, blood and umbilical cord blood. Now baby teeth have been proven to provide an abundant source of adult stem cells with the potential to treat and cure a vast number of illnesses and diseases.

The pulp of children’s baby teeth generally contains a range of valuable cells including:

Mesenchymal stem cells
. Cells with the ability to develop into a wide range tissues

Mesenchymal stem cells
. Cells with the ability to develop into a wide range tissues

Chondrocytes
. Cells with the ability to generate cartilage and therefore ideal for arthritis or joint injuries

Chondrocytes
. Cells with the ability to generate cartilage and therefore ideal for arthritis or joint injuries

Osteoblasts. 
Cells with the ability to generate bone

Osteoblasts. 
Cells with the ability to generate bone

Adipocytes. 
Cells with the ability to repair damaged cardiac tissue for example after a heart attack. They are also ideal for reconstructive surgery of the face.

Adipocytes. 
Cells with the ability to repair damaged cardiac tissue for example after a heart attack. They are also ideal for reconstructive surgery of the face.

 

The BioEden process collects all the cells potentially contained within the pulp area of the tooth at the time of processing.
The isolation of stem cells from teeth is a patent protected process owned by BioEden.

What happens if you cannot extract any tooth cells?

We will send you a letter immediately informing you that the process has been unsuccessful. If your child still has viable teeth left, we will complete the process again free as part of our service.

Can I donate some of my child’s cells to research?

When you apply for BioEden membership, you will be offered the opportunity to consent to donate any excess tooth cells. BioEden will provide these cells to leading academic and clinical research centres to help further the progression of this technology to useful clinical applications. BioEden will only provide cells to researchers that have full ethical approval for their research and will be guided by our Advisory team as to the most appropriate research to support. The cells will be donated in accordance with strict regulatory guidelines and anonymity of the donor will be strictly assured at all times.

Donation of cells is an entirely opt in service. If you choose not to give consent to donate, BioEden will simply store the cells for your child.

Who owns my child’s tooth cells?

Ownership of the child’s tooth cells belongs to the parent or legal guardian until the child’s 18th birthday. Then full ownership is passed to the donor.

Can I send any of my child’s teeth that have fallen out?

There are 12 usable teeth. Those are the Central Incisors; Lateral Incisors; and Canines. These are the top front six teeth and the lower front six teeth. There’ll be a diagram identifying these in your collection kit. However we accept molars if all others are already lost.

What happens if my child’s tooth falls out before the collection kit arrives?

Simply place the tooth in a cup of milk in the refrigerator. If you are not yet a member, call us on 0208 4770 336 to complete your application process and provide payment in full. We will then arrange for the collection kit to be sent to you within 24 hours. If you are already a member, call us on 0208 4770 336 to find out how soon your collection kit will arrive.

What if my child has no more viable teeth?

If we have failed to isolate any tooth cells from your child’s tooth, and we verified there are no more viable teeth left in the child’s mouth, we will refund you in full less £250 to cover the costs of postage and packing.

How long does it take for my child’s tooth cells to be frozen?

We will isolate the cells from the tooth within 24 hours of receiving it. Upon a successful isolation following our stringent procedures and within Human Tissue Authority Certification guidelines, we will cryogenically store the cells under your unique customer reference number. The entire BioEden tooth cell harvesting process should take 12-21 days.

What is the process?

Don’t wait until your child starts to lose their teeth before you make your decision. Join now and follow our simple 3 step process to ensure you’re immediately prepared to safely return the teeth to our nearest laboratory.

Always ensure that your child brushes their teeth regularly, (at least twice a day) and uses a mouthwash.

Step 1 – Tooth Collection

Join now, and we will send you a tooth collection kit. The tooth collection kit includes easy to follow instructions. Please read these prior to the tooth falling out or being extracted. The time immediately after the tooth has fallen out or has been extracted is critical.

Carefully following the instructions, the tooth must be placed and packaged in the collection box provided. You then contact us, and we arrange for the kit to be shipped and received at the BioEden laboratory within 48 hours to maximise chances of a successful isolation of the valuable tooth cells.

Within 7 days of the tooth falling out, please arrange a blood sample taken from your child and returned to us in the provided blood collection packaging.

Step 2 – Tooth Cell Isolation

When the tooth is received at the laboratory, our scientists work swiftly to collect the cellular material. Once the tooth cells are isolated, we confirm the health and viability of the cells.

Step 3 – Tooth Cell Storage

Once we have a guaranteed number of viable, uncontaminated tooth cells, suitable for healthy growth and future treatment, they are cryogenically stored for your family’s future. Every tooth cell batch is divided into two separate samples, then cryopreserved.

Our patented process allows us to keep these valuable tooth cells stored well into the adult life of the donor. This secures the potential for the treatment of illness and disease at a time when they are needed most.

We understand your continued interest in your investment, so we continually update all our customers on the latest advances in the field of stem cell research and application. We also regularly check all our processes to ensure we constantly maintain standards and operate within stringent regulatory guidelines.

In depth

What are stem cells?

Stem cells are of significant scientific interest and the subject of an ever increasing amount of research aiming to apply stem cells as medical therapies for the regeneration of human tissue. Stem cells are specialised cells which have the ability to replicate and transform into a range of different tissue and organ specific cell types. Stem cell therapy involves the delivery of cells to augment, replace or initiate the production of essential molecules or matrix from cells that are missing or damaged due to disease, ageing or trauma. Currently, the most common forms of cell therapy include blood and platelet transfusions and bone marrow transplants.

Bone marrow transplantation is a well established medical procedure successfully employed in the treatment of a variety of cancers and other serious diseases. This work was pioneered at the Fred Hutchinson Cancer Research Center from the 1950s through the 1970s and led by Dr. E. Donnall Thomas, whose work was later recognized with a Nobel Prize in Physiology or Medicine in 1990. According to the International Bone Marrow Transplant Registry, over 45,000 bone marrow and other hematopoietic (blood) stem cell transplant procedures were performed worldwide in 2002.

This has led many researchers to believe that stem cells have tremendous promise in the treatment of diseases other than those currently addressed by stem cell therapies. Researchers have reported progress in the development of new therapies utilizing stem cells for the treatment of cancer, neurological, immunological, genetic, cardiac, pancreatic, liver and degenerative diseases.

The success of current and emerging stem cell therapies is dependent on the presence of a rich and abundant source of stem cells. Umbilical cord blood is a source for one type of stem cell. The practice of cord blood collection has grown information about the potential therapeutic value of stem cells has become more widely known and accepted, following the first successful cord blood transplant performed in 1988.

Whilst cord blood is a rich source of hematopoietic stem cells, it does not contain significant quantities of mesenchymal stem cells (MSCs). MSCs are multipotent cells (cells that can give rise to diverse cell types in response to appropriate environmental cues). They have been shown to differentiate into bone cells (osteoblasts), fat cells ( adipocytes), liver cells (hepatocytes) and cartilage cells (chondrocytes) as well as muscle cells (myocytes) and nerve cells (neurons). This means they have enormous potential for future therapeutic use.

What is the difference between autologous and allogeneic, and how do they compare?

BioEden only offers the storage of cells for 100% autologous use. An autologous stem cell transplant uses the patient’s own stem cells. Advantages over Allogeneic stem cell transplant includes; no immune reaction or tissue rejection of the cells, no immunosuppressive therapy needed and significantly reduced risk of transmission of communicable diseases.

What is the process?

Don’t wait until your child starts to lose their teeth before you make your decision. Join now and follow our simple 3 step process to ensure you’re immediately prepared to safely return the teeth to our nearest laboratory.

Always ensure that your child brushes their teeth regularly, (at least twice a day) and uses a mouthwash.

Step 1 – Tooth Collection

Join now, and we will send you a tooth collection kit. The tooth collection kit includes easy to follow instructions. Please read these prior to the tooth falling out or being extracted. The time immediately after the tooth has fallen out or has been extracted is critical.

Carefully following the instructions, the tooth must be placed and packaged in the collection box provided. You then contact us, and we arrange for the kit to be shipped and received at the BioEden laboratory within 48 hours to maximise chances of a successful isolation of the valuable tooth cells.

Within 7 days of the tooth falling out, please arrange a blood sample taken from your child and returned to us in the provided blood collection packaging.

Step 2 – Tooth Cell Isolation

When the tooth is received at the laboratory, our scientists work swiftly to collect the cellular material. Once the tooth cells are isolated, we confirm the health and viability of the cells.

Step 3 – Tooth Cell Storage

Once we have a guaranteed number of viable, uncontaminated tooth cells, suitable for healthy growth and future treatment, they are cryogenically stored for your family’s future. Every tooth cell batch is divided into two separate samples, then cryopreserved.

Our patented process allows us to keep these valuable tooth cells stored well into the adult life of the donor. This secures the potential for the treatment of illness and disease at a time when they are needed most.

We understand your continued interest in your investment, so we continually update all our customers on the latest advances in the field of stem cell research and application. We also regularly check all our processes to ensure we constantly maintain standards and operate within stringent regulatory guidelines.

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"…building an organ that is a match for you, is available for you, is something that wasn’t even fathomable ten or 15 years ago…"

US Scientist Dr Dorris Taylor on her research work in building a human heart

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